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On the surface, Jerry Stahl (Ben Stiller) seems to have it all. A successful career as a top Hollywood television scriptwriter earning $5,000 a week, married to beautiful British television executive, Sandra (Elizabeth Hurley) (albeit a marriage of convenience), and a baby on the way. But behind the glossy facade lies a desperate junkie whose life is fast spiralling out of control. Having checked in a rehab clinic in the Arizona desert, Jerry starts a torrid affair with Kitty, (Maria Bello) a hardened but attractive recovering addict like himself, and together they face the challenging journey towards recovery in search of a brighter future...